Chemotherapy of Prostatic Adenocarcinoma : State of the Art 2019
PDF

Keywords

Adénocarcinome
Prostate
Chimiothérapie

Categories

How to Cite

1.
Essadi I, Lalya I, Kaakoua M, El Omrani A, Khouchani M, Belbaraka R. Chemotherapy of Prostatic Adenocarcinoma : State of the Art 2019. Integr J Med Sci [Internet]. 2019 Sep. 28 [cited 2022 Oct. 5];6. Available from: https://www.mbmj.org/index.php/ijms/article/view/101

Abstract

Prostate cancer is a heterogeneous disease, with different clinical-biological and evolutionary aspects. Most often it is a disease with indolent evolution. Chemotherapy has long been a therapy of last resort in the treatment of prostate cancer. Deploying chemotherapy in this context certainly implied the failure of all possibilities of hormonal manipulation. Thus, antineoplastic chemotherapy was first proposed in metastatic situations, with resistance to castration. Many molecules have confirmed the effectiveness of chemotherapy in this indication. Several phase III trials have placed chemotherapy as a serious option in less advanced situations, with very encouraging results in terms of survival and quality of life. Chemotherapy is currently considered as a therapeutic weapon that should be included in the management strategy, after discussion in a multidisciplinary consultation meeting. Through this review, we will try to establish the state of the art of the use of antineoplastic chemotherapy in prostatic adenocarcinoma in 2018, in metastatic (de novo or in a phase of resistance to castration), localized, or locally advanced situations.

https://doi.org/10.15342/ijms.v6ir.292
PDF

References

Siegel RL, Miller KD, Jemal A. Cancer statistics, 2016. CA Cancer J Clin. Jan-Feb 2016; 66(1):7–30. https://doi.org/10.3322/caac.21332

Registre des cancers de la région du grand Casablanca pour la période 2008-2012 (édition 2016). [Accessed 02 Jul 2021]. Available From: https://www.contrelecancer.ma/site_media/uploaded_files/RCRGC.pdf

Huggins C, Hodges CV. Studies on prostatic cancer: I. The effect of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate. CA Cancer J Clin. Jul-Aug 1972; 22(4):232-40. https://doi.org/10.3322/canjclin.22.4.232

Essadi I, Lalya I , Elharrech Y, Ghoundale O, Touiti D. Metastatic Castration Resistant Prostate Cancer : For when a “Piecemeal” Therapeutic Strategy ? BAOJ Med Nursing. 2015 1: 2 1: 009.

Jacques M, Dimitri D, Eugeniu B, Floriant S, Philippe B, Oudard S. Chimiothérapie du cancer de la prostate. Presse Med. 2008 May; 37(5): 814–820. https://doi.org/10.1016/j.lpm.2007.07.019

Sridhar SS, Freedland SJ, Gleave ME, Higano C, Mulders P, Parker C, et al. Castration-resistant prostate cancer: from new pathophysiology to new treatment. Eur Urol. 2014 Feb; 65(2): 289–299. https://doi.org/10.1016/j.eururo.2013.08.008

Mohler JL. Castration-recurrent prostate cancer is not androgen- independent. Adv Exp Med Biol. 2008; 617:223-34. https://doi.org/10.1007/978-0-387-69080-3_21

Tannock IF, Osoba D, Stockler MR, Ernst DS, Neville AJ, Armitage GR, et al. Chemotherapy with mitoxantrone plus prednisone or prednisone alone for symptomatic hormone-resistant prostate cancer: a Canadianrandomized trial with palliative end points. J Clin Oncol.1996 Jun;14(6): 1756-64. https://doi.org/10.1200/jco.1996.14.6.1756

Tannock IF, De Wit R, Berry WR, Horti J, Pluzanska A, Chi KN, et al. Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer. N Engl J Med. 2004 Oct 7; 351(15): 1502–1512. https://doi.org/10.1056/nejmoa040720

Petrylak DP, Tangen CM, Hussain MH, Lara PN Jr, Jones JA, Taplin ME, et al. Docetaxel and estra- mustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer. N Engl J Med. 2004 Oct 7; 351(15): 1513–20. https://doi.org/10.1056/nejmoa041318

Oudard S, Banu E, Banu A, Scotte F, Levy E, Medioni J et al. Docetaxel versus mitoxantrone as first-line chemotherapy for hormone- refractory prostate cancer (HRPC) patients. A meta-analysis of 3-year overall survival results. J Clin Oncol. 2005; 23(16): 4634. [Accessed 02 Jul 2021]. Available From: https://ascopubs.org/doi/abs/10.1200/jco.2005.23.16_suppl.4634

Ohlmann CH, Engelmann UH, Heidenreich A. Second-line chemotherapy with docetaxel for prostate-specific antigen (PSA) relapse in men with hormone-refractory prostate cancer (HRPCA) previously treated with docetaxel- based chemotherapy. J Clin Oncol. 2006;23(16):248.[Accessed 02 Jul 2021]. Available From: https://ascopubs.org/doi/abs/10.1200/jco.2005.23.16_suppl.4682

Antonarakis ES, Eisenberger MA. Phase III trials with docetaxelbased combinations for metastatic castration-resistant prostate cancer: time to learn from past experiences. J Clin Oncol. 2013 May 10; 31(14): 1709-12. https://doi.org/10.1200/jco.2013.48.8825

Mita AC, Denis LJ, Rowinsky EK, Debono JS, Goetz AD, Ochoa L, et al. Phase I and pharmacokinetic study of XRP6258 (RPR 116258A), a novel taxane, administered as a 1-hour infusion every 3 weeks in patients with advanced solid tumors. Clin Cancer Res; 2009 Jan15; 15(2): 723–730. https://doi.org/10.1158/1078-0432.ccr-08-0596

de Bono JS, Oudard S, Ozguroglu M, Hansen S, Machiels J, Kocak I, et al.Prednisone plus cabazitaxel or mitoxantrone for metastatic castrationresistant prostate cancer progressing after docetaxel treatment: a randomised open- label trial. Lancet. 2010 Oct 2; 376(9747): 1147-54. https://doi.org/10.1016/s0140-6736(10)61389-x

Oudard S, Fizazi K, Sengeløv L, Daugaard G, Saad F, Hansen S, et al. Cabazitaxel Versus Docetaxel As First-Line Therapy for Patients With Metastatic Castration-Resistant Prostate Cancer: A Randomized Phase III Trial-FIRSTANA. J Clin Oncol. 2017 Oct 1;35(28):3189-3197. https://doi.org/10.1200/jco.2016.72.1068

Abratt RP, Brune D, Dimopoulos MA, Kliment J, Breza J, Selvaggi FP et al. Randomised phase III study of intravenous vinorelbine plus hormone therapy versus hormone therapy alone in hormone refractory prostate cancer. Ann Oncol. 2004 Nov;15(11):1613-21. https://doi.org/10.1093/annonc/mdh429

Zampino MG, Verri E, Locatelli M, Curigliano G, Ascione G, Sbanotto A et al. Vinorelbine based chemotherapy in hormone-refractory prostate cancer. Anticancer Res. May-Jun 2006; 26(3B): 2375-80. .[Accessed 02 Jul 2021]. Available From: https://ar.iiarjournals.org/content/26/3B/2375

Markowski MC , Carducci MA. Early use of chemotherapy in metastatic prostate cancer. Cancer Treat Rev. 2017 Apr;55: 218-224. https://doi.org/10.1016/j.ctrv.2016.09.017

Gravis G, Fizazi K, Joly F, Oudard S, Priou F, Esterni B, et al. Androgen-deprivation therapy alone or with docetaxel in non-castrate metastatic prostate cancer (GETUG-AFU 15): a randomised, open-label, phase 3 trial. Lancet Oncol. 2013 Feb; 14(2):149–58. https://doi.org/10.1016/s1470-2045(12)70560-0

Sweeney CJ, Chen YH, Carducci M, Liu G, Jarrard DF, Eisenberger M, et al. Chemohormonal therapy in metastatic hormone-sensitive prostate cancer. N Engl J Med. 2015 Aug 20;373(8):737–46. https://doi.org/10.1056/nejmoa1503747

Gravis G, Boher JM, Joly F, Soulié M, Albiges L, Priou F, et al. Androgen Deprivation Therapy (ADT) plus docetaxel versus ADT alone in metastatic non castrate prostate cancer: impact of metastatic burden and long term survival analysis of the randomized phase 3 GETUG-AFU15 Trial. Eur Urol. 2016 Aug; 70(2):256-62. https://doi.org/10.1016/j.eururo.2015.11.005

James ND, Sydes MR, Clarke NW, Mason MD, Dearnaley DP, Spears MR, et al. Addition of docetaxel, zoledronic acid, or both to first-line long-term hormone therapy in prostate cancer (STAMPEDE): survival results from an adaptive, multiarm, multistage, platform randomised controlled trial. Lancet. 2016 Mar 19; 387(10024): 1163-77. https://doi.org/10.1016/s0140-6736(15)01037-5

Ahlgren GM, Flodgren P, Tammela TL, Kellokumpu-Lehtinen P, Borre M, Angelsen A, et al. Docetaxel versus surveillance after radical prostatectomy for high-risk prostate cancer: results from the prospective randomized, open-label phase 3 Scandinavian Prostate Cancer Group 12 trial. Eur Urol. 2018 Jun; 73(6): 870-876. https://doi.org/10.1016/j.eururo.2018.01.012.

Lin D, Garzotto M, Aronson W, et al. VA CSP#553 chemotherapy after prostatectomy (CAP) for high risk prostate carcinoma: a phase III randomized study. J Urol. 2016 Apr;195(4) : e1071. https://doi.org/10.1016/j.juro.2016.03.129

Elaine LE, Glodé LM. Neoadjuvant and Adjuvant Hormonal and Chemotherapy for Prostate Cancer. Hematol Oncol Clin N Am. 2013 Dec; 27 (6):1189–1204. http://dx.doi.org/10.1016/j.hoc.2013.08.004

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright (c) 2019 Ismail Essadi et al.

Downloads

Download data is not yet available.