Gastric Schwannoma: A Postoperative Surprise - A Case Report


Gastric schwannoma
Submucosal tumor
Partial gastrectomy
S-100 protein


How to Cite

Ait Ali A, Essarghini M, Hajjouji A, Sair K. Gastric Schwannoma: A Postoperative Surprise - A Case Report. Integr J Med Sci [Internet]. 2014 Jun. 20 [cited 2024 Apr. 20];1:23-5. Available from:


Gastric Schwannoma is a rare, slow-growing, and clinically non-specific submucosal tumor, originating from Schwann cells with an excellent prognosis after surgical resection. We report a clinical case of a patient presented with gastric schwannoma revealed by non-specific gastric signs and of which the definitive diagnosis is done through immunohistochemistry of the resected specimen, showing strong S100 protein positivity. The evolution is favorable after partial gastrectomy with a decline of two years. Through this case, we are trying to trace the rarity, strong similarities with gastric stromal tumors, and especially, the weak index of suspicion for this diagnosis.


Melvin WS, Wilkinson MG. Gastric schwannoma. Clinical and pathologic considerations. Am Surg. 1993 May; 59(5):293-6. [Accessed 28th May 2021]. Available from:

Zuo HD, Zhang X, Zhai ZH. Nerve Sheath Tumor of Stomach: Two Cases Report. J Med Cases. 2012; 3(1):68-72.

Daimaru Y, Kido H, Hashimoto H, Enjoji M. Benign schwannoma of the gastrointestinal tract: a clinicopathologic and immunohistochemical study. Hum Pathol. 1988 Mar; 19(3):257-64.

Woodruff JM, Selig AM, Crowley K, Allen PW. Schwannoma (Neurilemoma) with Malignant Transformation A Rare, Distinctive Peripheral Nerve Tumor. Am J Surg Pathol. 1994 Sep; 18(9):882-95.

Sarlomo-Rikala M, Miettinen M. Gastric schwannoma--a clinicopathological analysis of six cases. Histopathology. 1995 Oct; 27(4):355-60.

Yoon W, Paulson K, Mazzara P, Nagori S, Barawi M, Berri R. Gastric Schwannoma: A Rare but Important Differential Diagnosis of a Gastric Submucosal Mass. Case Rep Surg. 2012; 2012: 280982.

Raber MH, des Plantes CMZ, Vink R, Klaase JM. Gastric schwannoma presenting as an incidentaloma on CT-scan and MRI. Gastroenterology Res. 2011 Dec; 3(6):276-280.

Kessler W, Schreiber A, Glitsch A, Evert M, Puls R, Patrzyk M, et al. [Gastric schwannoma: a" typical" clinical course?]. Chirurg. 2009 Jan; 80(1):62-4.

Voltaggio L, Murray R, Lasota J, Miettinen M. Gastric schwannoma: a clinicopathologic study of 51 cases and critical review of the literature. Hum Pathol. 2012 May; 43(5):650-9.

Fujiwara S, Nakajima K, Nishida T, Takahashi T, Kurokawa Y, Yamasaki M, et al. Gastric schwannomas revisited: has precise preoperative diagnosis become feasible? Gastric Cancer. 2013 Jul; 16(3):318-23.

Sadok Boudaya M, Dechaud C, Gossot D, Validire P, Magdeleinat P, Moretti JL. [Benign schwannoma with high uptake of 18 fluorodeoxglucose (PET-Scan)]. Rev Mal Respir. 2009 Jan; 26(1):63-5.

Hong HS, Ha Hk, Won HJ, Byun JH, Shin YM, Kim AY, et al. Gastric schwannomas: radiological features with endoscopic and pathological correlation. Clin Radiol. 2008; May 63(5):536-42.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright (c) 2014 Abdelmounaim Ait Ali et al.


Download data is not yet available.


Metrics Loading ...