Rheumatoid Arthritis in Morocco: Past and Present


Rheumatoid Arthritis
Early Arthritis
Undifferentiated Polyarthritis


How to Cite

Hajjaj-Hassouni N. Rheumatoid Arthritis in Morocco: Past and Present. Integr J Med Sci [Internet]. 2017 May 3 [cited 2022 Dec. 6];4:43-6. Available from: https://www.mbmj.org/index.php/ijms/article/view/55


In Morocco, the socio-economic impact of the disease is significant. The difficulties of the patients in accessing treatment, the consequences on their personal and familial life have been highlighted. Among them, the negative consequences on the schooling of female children are significant. Because of this, prevention and information are of high importance in the management of patients as well as the use of treatment at a « reasonable cost ». Moreover, the comparison of the data, thanks to inclusion in international studies, has allowed the demonstration of the severity of the disease, mainly due to delayed diagnosis, delay in referral to rheumatologists, and low socioeconomic status. The setting up of a cohort of recent polyarthritis followed over a two-year period has highlighted the importance of very early diagnosis and management and the resulting
significant improvement in the prognosis of the disease. It has been followed by the setting up of a cohort of recent polyarthritis the objective of which is a follow-up of recent polyarthritis progressing less than one year over a period of ten years and the constitution of a database in order to allow studies on the diagnosis, prognosis, epidemiology and socioeconomic impact of recent polyarthritis in Morocco as well as the use of affordable economic treatment.



Pedersen JK, Kjaer NK, Svendsen AJ, Hørslev-Petersen K. Incidence of rheumatoid arthritis from 1995 to 2001: impact of ascertainment from multiple sources. Rheumatol Int. 2009 Feb; 29(4): 411–15. https://doi.org/10.1007/s00296-008-0713-6

Alamanos Y, Voulgari PV, Dross AA. Incidence and prevalence of rheumatoid arthritis, based on the 1987 American College of Rheumatology criteria: a systematic review. Semin Arthritis Rheum. 2006 Dec; 36 (3):182-8. https://doi.org/10.1016/j.semarthrit.2006.08.006

Kalla AA, Tikly M. Rheumatoid arthritis in the developing world. Best Pract Res Clin Rheumatol. 2003 Oct; 17(5): 863–75. https://doi.org/10.1016/s1521-6942(03)00047-0

Kobelt G, Lindgren P, Lindroth Y, Jacobson L, Eberhardt K. Modelling the effect of function and disease activity on costs and quality of life in rheumatoid arthritis. Rheumatology (Oxford). 2005 Sep; 44(9):1169-75. https://doi.org/10.1093/rheumatology/keh703

Scott DL, Wolfe W, Huizinga TW . Rheumatoid arthritis. Lancet. 2010; Sep 25; 376: (9746): 1094–1108. https://doi.org/10.1016/s0140-6736(10)60826-4

Smolen JS, Aletaha D, McInnes IB. Rheumatoid arthritis. Lancet. 2016 Oct 22; 388 (10055): 2023–38. https://doi.org/10.1016/s0140-6736(16)30173-8

Naranjo A, Toloza S, Guimaraes da Silveira I, Lazovskis J, Hetland ML, Hamoud H, et al. Smokers and nonsmokers with rheumatoid arthritis have similar clinical status: data from the multinational QUEST-RA database. Clin Exp Rheumatol. Nov-Dec 2010; 28(6):820-7.

Van Steenbergen HW, Huizinga TW, van der Helm-van Mil AH. The preclinical phase of rheumatoid arthritis: what is acknowledged and what needs to be assessed? Arthritis and Rheum. 2013 Sep; 65(9): 2219–32. https://doi.org/10.1002/art.38013

Geoffroy H, Lalu P, Kouhen C, Laurent G. La Polyarthrite Chronique Evolutive au Maroc (106 cas). Maroc Med. 1964 Apr; 43: 343-72.

Hajjaj-Hassouni N, Hassouni F, Guedira N. Prévalence des maladies rhumatismales observées au Maroc. Rev Rhum Paris. 1998;761.

Benamour S, Zeroual B, Fares L, El Kabli H, Bettal S. Rheumatoid arthritis in Morocco. A propos of 404 observations. Rev Rhum Mal Osteoartic. 1992 Dec; 59(12):801-7.

Hajjaj-Hassouni N, Hassouni F, N. Guedira, Lazrak N. La polyarthrite rhumatoïde au Maroc. A propos de 444 cas. Sem Hôp Paris. 1994; 70 (1-2): 12-20.

Rkain H, Allali F, Jroundi I, Hajjaj-Hassouni N. Socioeconomic impact of rheumatoid arthritis in Morocco. Joint Bone Spine. 2006 May; 73(3): 278-83. https://doi.org/10.1016/j.jbspin.2005.03.021

] Sokka T, Kautiainen H, Pincus T, Verstappen SM, Aggarwal A, Alten R, et al. Work disability remains a major problem in rheumatoid arthritis in the 2000s: data from 32 countries in the QUEST-RA study. Arthritis Res Ther. 2010; 12(2):R42. https://doi.org/10.1186/ar2951

Jawaheer D, Olsen J, Lahiff M, Forsberg S, Lähteenmäki J, da Silveira IG, Et al. Gender, body mass index and rheumatoid arthritis disease activity: results from the QUEST-RA Study. Clin Exp Rheumatol. Jul-Aug 2010; 28 (4):454-61.

Badsha H, Fathi NA, Hamoud H, Hajjaj-Hassouni N, Abda E, Ebraheam Z, et al. Profile of patients with rheumatoid arthritis in rarely-reported locations: North Africa. Ann Rheum Dis. 2009;68(Suppl3):352.

Dougados M, Soubrier M, Antunez A, Balint P, Balsa A, Buch MH, et al. Prevalence of comorbidities in rheumatoid arthritis and evaluation of their monitoring: results of an international, cross-sectional study (COMORA). Ann Rheum Dis. 2014 Jan;73(1):62-8. https://doi.org/10.1136/annrheumdis-2013-204223

Benbouazza K, Benchekroun B, Rkain H, Amine B, Bzami F, Benbrahim L, et al. Profile and course of early rheumatoid arthritis in Morocco: a two-year follow-up study. BMC Musculoskelet Disord .2011 Nov 23; 12:266. https://doi.org/10.1186/1471-2474-12-266

Atouf O, Benbouazza K, Brick C, Bzami F, Bennani N, Amine B,et al. HLA polymorphism and early rheumatoid arthritis in the Moroccan population. Joint Bone Spine. 2008 Oct; 75(5):554-8. https://doi.org/10.1016/j.jbspin.2008.01.027

Minichiello É, Semerano L, Boissier MC. Time trends in the incidence, prevalence, and severity of rheumatoid arthritis: A systematic literature review. Joint Bone Spine. 2016 Dec; 83(6):625-630. https://doi.org/10.1016/j.jbspin.2016.07.007

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Copyright (c) 2017 Najia Hajjaj-Hassouni


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