Malignant Orbital Tumors in Children: A Series of 4 Cases
PDF

Keywords

Pediatric
Malignant
Tumor
Orbit

Categories

How to Cite

1.
Alami F, Imdary I, El Hassan A, Chefchaouini MC, Berraho A. Malignant Orbital Tumors in Children: A Series of 4 Cases. Integr J Med Sci [Internet]. 2014 Dec. 21 [cited 2024 Mar. 29];1:44-8. Available from: https://www.mbmj.org/index.php/ijms/article/view/12

Abstract

Introduction: Malignant tumors in children are rare but serious conditions as they can impair function and survival. Tumors in pediatric patients can originate from the orbit. Rarely, the tumor spreads to the adjacent areas and occasionally it may metastasize.
Objectives: The objective of this study is to present the common symptoms and the clinical and radiological characteristics of the most common malignant orbital tumors in children.
Materials and methods: Through the discussion of 4 clinical cases of children presenting with exophthalmos due to a tumor, the authors highlight that clinical symptoms are usually less specific and that imaging has an important role in diagnosis, determining location, and local and regional expansion of the tumor in order to find the adequate therapy.
Results: Our patients' ages ranged from 2 to 5 years. The revealing sign in each case was unilateral exophthalmos due to a tumor, which could only be reduced minimally or not at all. Its evolution has been rapidly progressive. Orbital imaging and histologic study, if a biopsy was possible, allowed guiding the positive diagnosis of the malignant nature and its local and regional spreading, as well as the adequate treatment.
Conclusion: Orbital tumors are rare in the pediatric population. However, due to recent remarkable progress obtained through both complementary diagnostic tools and treatments, these malignancies deserve the attention of both ophthalmologists and pediatricians.

https://doi.org/10.15342/ijms.v1i2.6
PDF

References

Mejdoubi M, Arne JL, Sevely A. [Orbital tumors in children: CT and MR imaging features]. J Radiol. 2007 Dec; 88(12):1855-64. https://doi.org/10.1016/s0221-0363(07)78363-4

Shields JA, Shields CL, Scartozzi R. Survey of 1264 patients with orbital tumors and simulating lesions: The 2002 Montgomery Lecture, part 1. Ophthalmology. 2004 May; 111(5):997-1008. https://doi.org/10.1016/j.ophtha.2003.01.002

Stockl FA, Dolmetsch AM, Saornil MA, Font RL, Burnier MN Jr. Orbital granulocytic sarcoma. Br J Ophthalmol . 1997 Dec; 81(12):1084-8. https://doi.org/10.1136/bjo.81.12.1084

Ali MJ, Honavar SG, Reddy VA. Orbital retinoblastoma: Present status and future challenges - A review. Saudi J Ophthalmol. 2011 Apr; 25(2):159-67. https://doi.org/10.1016/j.sjopt.2010.10.010

Gorospe L, Royo A, Berrocal T, Garcia-Raya P, Moreno P, Abelairas J. Imaging of orbital disorders in pediatric patients. Eur Radiol. 2003 Aug; 13(8):2012-26. https://doi.org/10.1007/s00330-002-1738-y

De Meux PdL. Ophtalmologie pédiatrique: Elsevier Masson; 2003. [Accessed 28th May 2021]. Available From: https://www.elsevier-masson.fr/ophtalmologie-pediatrique-9782294008009.html

Renard C, Girard S, Pracros JP, Dijoud F, Andre JM, Mialou V, et al. [Granulocytic sarcoma, a diagnostic challenge: 3 pediatric cases]. Arch Pediatr. 2010 Feb; 17(2):149-53. https://doi.org/10.1016/j.arcped.2009.10.018

Blanchard S, Labalette P, Jourdel D, Dedes V, Leleu X, Dillie AF, et al. [Orbital granulocytic sarcoma revealing acute myeloblastic syndrome: a case study]. J Fr Ophtalmol. 2004 Feb; 27(2):184-7. https://doi.org/10.1016/s0181-5512(04)96117-7

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright (c) 2014 Fadoua Alami et al.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...